I am stuffing a Coyote into my 70 Mach 1, not a 66 but should give you an idea of what you are getting yourself into. I am using the front clip and suspension from Total Control Products, another option to MTF, Heidts, Detroit Speed and others.
Unless you have a large budget, don't go down this road. I used a low mileage donor for my engine and transmission and I am approaching $40K in part plus the car. Don't get me wrong, the Coyote is a great engine, just difficult to fit into a vintage Mustang. I have found that many parts are unique and expensive, that pushes the cost up quickly. I am sure there are ways to get it done less expensively, but that would take some research. When I started, I chose a few vendors and created a spread sheet for cost comparison. At the time TCP appeared competitive, now there are options that are cheaper. However, the components, like Wilwood brakes, Strange 3rd member, etc. are known quality pieces, so I have found that quality costs.
The link to my build thread is in my signature line.