From what I gather they work well for vertical imbalance but are ineffective for lateral imbalance. Big truck tires need them as you could not put enough weight on the wheels. I can see where they would work for motorcycle tires as well since the tires are relatively skinny compared to the overall height. They are kind of like a Philips head screw driver, they work really well on the screws for which they were designed, but don't work on all screws.They have ran them in large tires for years. My dad was a diesel mechanic and told me about it years ago when I was trying to get some large tires to balance on my lifted truck. I run them in my motorcycles and it made a HUGE difference the first time I used them. Had a V Rod and would get bad wobbles at around 90, with the beads I could easily hit 120+.